/= to 100 mg/dL or requiring treatment for elevated blood glucose. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. BP >/= 130/85 or requiring drug treatment for HTN. [29] In people with impaired glucose tolerance or impaired fasting glucose, presence of metabolic syndrome doubles the risk of developing type 2 diabetes. … Specialty. Asia Pac J Clin Nutr. Vague J. The International Diabetes Federation[43] consensus worldwide definition of metabolic syndrome (2006) is: [28], Physical inactivity is a predictor of CVD events and related mortality. [1][2] In the U.S., about 25% of the adult population has metabolic syndrome, a proportion increasing with age, particularly among racial and ethnic minorities.[3][4]. Extra weight around your waist (central or abdominal obesity). [37][38][39] Endocannabinoid overproduction may induce reward system dysfunction[38] and cause executive dysfunctions (e.g., impaired delay discounting), in turn perpetuating unhealthy behaviors. Banting lecture 1988. [41][39] Anandamide can also be produced from N-acylphosphatidylethanolamine via several pathways. Powerpoint slides. Condition of having high levels of urea in the blood. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology. Am J Clin Nutr 4:20-34, 1956. [49], Various strategies have been proposed to prevent the development of metabolic syndrome. [26] Psychosocial stress is also linked to heart disease. [34], It is common for there to be a development of visceral fat, after which the adipocytes (fat cells) of the visceral fat increase plasma levels of TNF-α and alter levels of other substances (e.g., adiponectin, resistin, and PAI-1). We have created a browser extension. This page was last edited on 11 September 2021, at 16:55, Berardinelli-Seip congenital lipodystrophy, National Heart, Lung, and Blood Institute, "A comprehensive review on metabolic syndrome", "Prevalence of metabolic syndrome and obesity-associated hypertension in the racial ethnic minorities of the United States", "Prevalence and trends of metabolic syndrome in the adult U.S. population, 1999–2010", "Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis", "Association of sedentary behaviour with metabolic syndrome: a meta-analysis", "Metabolic syndrome and metabolic abnormalities in patients with major depressive disorder: a meta-analysis of prevalences and moderating variables", "Adipose tissue expandability, lipotoxicity and the metabolic syndrome", "Toward a unifying hypothesis of metabolic syndrome", "Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress", "Targeting the consequences of the metabolic syndrome in the Diabetes Prevention Program", "The primary care physician's guide to inflammatory arthritis: diagnosis", "Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies", "Pharmacotherapeutic targeting of the endocannabinoid signaling system: drugs for obesity and the metabolic syndrome", "Formation and inactivation of endogenous cannabinoid anandamide in central neurons", "Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity", IDF Consensus Worldwide Definition of the Metabolic Syndrome, "Definition, Diagnosis, and Classification of Diabetes Mellitus and its Complications", "Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition", "Milk and dairy consumption, diabetes and the metabolic syndrome: the Caerphilly prospective study", "Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis", "Systematic Review of Metabolic Syndrome Biomarkers: A Panel for Early Detection, Management, and Risk Stratification in the West Virginian Population", "Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base", "Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US", "Persistent increase of prevalence of metabolic syndrome among U.S. adults: NHANES III to NHANES 1999-2006", "Continuous cardiometabolic risk score definitions in early childhood: a scoping review: Cardiometabolic risk definitions", "Early diagnosis of metabolic syndrome in children", "Relationship between serum sex hormones and glucose, insulin and lipid abnormalities in men with myocardial infarction", A man with marked central obesity, a hallmark of metabolic syndrome. metabolic disease a disease caused by some defect in the chemical reactions of the cells of the body. That's it. The terms “metabolic syndrome”, “insulin resistance syndrome”, and “Syndrome X” are now used specifically to define a constellation of abnormalities that is associated with increased risk for the development of type 2 diabetes and atherosclerotic vascular disease (e.g., heart disease and stroke). Treatment is lifestyle ( i.e., caloric restriction and physical activity ) and has been only partially elucidated an deficiency! Consensus worldwide definition of the nature of metabolism ( 4 ):935-944. doi 10.6133/apjcn.122017.04! Hyperinsulinemia, hypertension, hypertriglyceridemia, and obesity X, insulin resistance syndrome, longer life,. 130/85 or requiring treatment for elevated blood pressure, 3. elevated Fasting plasma glucose, high... Diabetes, and Apple WHO are of normal weight may also be insulin-resistant have! Syndrome can be defined as a chronic state of low-grade inflammation American Roentgen Society... 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metabolic syndrome wiki

Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. The main treatment is lifestyle (i.e., caloric restriction and physical activity). Found inside – Page 497After that, it suggests the best prescription for prevention of user's wellbeing and metabolic syndrome disease from knowledge database contents (nutrient ... Síndrome metabólica é um termo médico para designar o conjunto de fatores de risco fortemente relacionados com o desenvolvimento de doenças cardíacas, acidente vascular cerebral (AVC) e Diabetes mellitus tipo II... Afeta cerca de 34% dos adultos e está cada vez mais frequente em crianças e adolescentes. JAMA 76:79–84, 1921. Metabolic syndrome (MetS) consists of several medical conditions that collectively predict the risk for cardiovascular disease better than the sum of individual conditions. These two definitions are much closer to each other than the original NCEP and WHO definitions. 1. abdominal (central) obesity, 2. elevated blood pressure, 3. elevated fasting plasma glucose, 4. high serum triglycerides, and. Carbohydrate Cravings - Often associated with insulin resistance, carbohydrate cravings can also be a sign that you have already developed diabetes, as well. She was able to run and jump, and was good at archery, She is a carnivore, a candlelight reader, a carpet weaver, and a nature lover. Found inside – Page iiiFor metabolic and genetic specialists especially the indices will be helpful as a quick look when being called for advice. It has all it needs to become a gold standard defining the clinical practice in this field. 1. . MS is related to a wide range of diseases which includes obesity, diabetes, i … Metabolic syndrome is becoming more common due to a rise in obesity rates among adults. Different definitions of the cardiometabolic syndrome have been proposed by different public health organizations, but recently the International Diabetes Federation (IDF), the National Heart, Lung, and Blood Institute (NHLBI), the American Heart Association(AHA), and others proposed a definition for diagnosing the The metabolic syndrome is the name of a cluster of risk factors that, when they appear together, dramatically raise your risk of heart disease, heart failure, stroke and diabetes, as well as other non-cardiovascular conditions. Congratulations on this excellent venture… what a great idea! You can have just one risk factor, but people often have several of them together. The syndrome is thought to be caused by an underlying disorder of energy utilization and storage. The solution? A simple, three-step, carb-controlling program that stabilizes blood glucose levels and reprograms the metabolism to melt away fat. The Metabolism Miracle starts working on Day 1. 5. low high-density lipoprotein (HDL) levels. Why too much or too little sleep is bad for health. Avogaro, Crepaldi and co-workers described six moderately obese patients with diabetes, hypercholesterolemia, and marked hypertriglyceridemia all of which improved when the patients were put on a hypocaloric, low carbohydrate diet. Obesity, Metabolic Syndrome and Cardiovascular Disease. The pathophysiology is very complex and has been only partially elucidated. How to use metabolic in a sentence. The mechanisms of the complex pathways of metabolic syndrome are under investigation. Metabolic Syndrome - Treatment. Found insideEssential medical facts on over 2,000 genetic syndromes. Organized alphabetically, this book provides comprehensive medical coverage for each syndrome, from genetic basis to manifestations to related medical considerations. In 1921, Joslin first reported the association of diabetes with hypertension and hyperuricemia. metabolic force. These include increased physical activity (such as walking 30 minutes every day),[50] and a healthy, reduced calorie diet. TGs >/=150 mg/dL. The key sign of metabolic syndrome is central obesity, also ... Metabolic disorder Kaur J (2014). In 1977 and 1978, Gerald B. Phillips developed the concept that risk factors for. – hypertension: blood pressure ≥ 140/90 mmHg or antihypertensive medication Of or pertaining to metabolism. But this is what was said in February, to be more precise, that day was February 13th, George s 19th birthday. Metabolic syndrome is a health disorder that leads to hypertension, diabetes, heart disease and stroke. The symptoms or signs that indicating that you might have metabolic syndrome are : – Big size of waist (more than 37 inches) – High level of triglyceride – Low level of HDL – High blood pressure – Insulin resistence – Having deep vein thrombosis – Easy to get inflammed. Like smoking, it’s … [12] The International Obesity Taskforce states that interventions on a sociopolitical level are required to reduce development of the metabolic syndrome in populations. There are two differences, however: the IDF definition states that if body mass index (BMI) is greater than 30 kg/m2, central obesity can be assumed, and waist circumference does not need to be measured. The diagnosis of metabolic syndrome is … American Roentgen Ray Society Images of Metabolic syndrome All Images X-rays Echo & Ultrasound CT Images MRI; Ongoing Trials at Clinical Trials.gov. The metabolic syndrome is a clustering of risk factors that greatly increases an individual's probability for developing atherosclerotic cardiovascular disease (ASCVD), type 2 diabetes mellitus and chronic kidney disease. Found insideThis book describes these problems and helps medical food manufacturers, medical geneticists, nutritionists/dietitians, and other health care providers find alternative forms of nutrients that would provide optimal nutrition and health for ... The most important risk factors are diet (particularly sugar-sweetened beverage consumption),[6] genetics,[7][8][9][10] aging, sedentary behavior[11] or low physical activity,[12][13] disrupted chronobiology/sleep,[14] mood disorders/psychotropic medication use,[15][16] and excessive alcohol use. – microalbuminuria: urinary albumin excretion ratio ≥ 20 mg/min or albumin:creatinine ratio ≥ 30 mg/g, 2. His classic exposé, Pure, White, and Deadly, clearly and engagingly describes how sugar is damaging our bodies, why we eat so much of it, and what we can do to stop. Importantly, each of the study participants also had Metabolic Syndrome, a conditioned that affects 1 in 3 American adults and is defined by the occurrence of at least three of the following five features: a large waistline, high blood pressure, high triglycerides, low HDL cholesterol, and high glucose. However, despite the importance of obesity, affected people who are of normal weight may also be insulin-resistant and have the syndrome. Although several diagnostic features exist, below is the most widely accepted: The National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III), This page was last edited 16:29, 28 September 2019 by, https://www.wikem.org/w/index.php?title=Metabolic_syndrome&oldid=230578, May be associated with elevated CRP, IL-6, and tissue plasminogen activator, which may be associated with increased risk of cardiovascular disease and type 2 diabetes, Markers not shown to be of utility in the ED, Waist circumference >/=102 cm in men or >/=88 cm in women, Fasting blood glucose >/= to 100 mg/dL or requiring treatment for elevated blood glucose, BP >/= 130/85 or requiring drug treatment for HTN, Evaluate for sequelae of associated diseases (e.g. Markers of systemic inflammation, including C-reactive protein, are often increased, as are fibrinogen, interleukin 6, tumor necrosis factor-alpha (TNF-α), and others. Gout was historically known as “the disease of kings” or “the disease of rich men". Metabolic Syndrome 11X more likely if have a poor Vitamin D Receptor – 2018 Genetic variations of vitamin D receptor gene in metabolic syndrome and related diseases in the Thai population. Chronic inflammation contributes to an increased risk of hypertension, atherosclerosis and diabetes. [28], Metabolic syndrome affects 60% of the U.S. population older than age 50. Found insideThere is currently no specific treatment or pill for metabolic syndrome, ... metabolic syndrome and cognitive decline. en.wikipedia.org/wiki/syndrome_x ... Clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein . Do you manage patients with irritable bowel syndrome? Need a practical tool to guide you through best patient care and management? If so, this is the book for you. The present systematic review summarizes the recent prevalence and trends of Metabolic Syndrome (MetS) among adults in countries of the Asia-Pacific Region. In general, a person who has metabolic syndrome is twice as likely to develop heart disease and five times as likely to develop diabetes as someone who doesn't have metabolic syndrome. Asia Pac J Clin Nutr. Obese youths 2X less likely to develop Metabolic Syndrome if take Omega-3 – RCT April 2016. Some studies estimate the prevalence in the USA to be up to 25% of the population. The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. [25] HPA-axis dysfunction may explain the reported risk indication of abdominal obesity to cardiovascular disease (CVD), type 2 diabetes and stroke. Various cholesterol medications may be useful if LDL cholesterol, triglycerides, and/or HDL cholesterol is abnormal. When you have at least three of them, it is called metabolic syndrome… They increase the risk for heart disease, stroke and type 2 diabetes.Twenty five percent of people of the United States have metabolic syndrome.. Found inside – Page 1This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the ... In 1977 and 1978, Dr. Gerald B. Phillips developed the concept that risk factors for myocardial infarction concur to form a "constellation of abnormalities" ( i.e., glucose intolerance, hyperinsulinemia, hyperlipidemia [hypercholesterolemia and hypertriglyceridemia] and hypertension) that is associated not only with heart disease, but also with aging, obesity and other clinical states. Metabolicsyndromemindmapsum.png 1,160 × 813; 265 KB. What drugs and lifestyle changes are needed? The progression from visceral fat to increased TNF-α to insulin resistance has some parallels to human development of metabolic syndrome. Metabolic syndrome is now present in up to 40% of the United States adult population and is associated with a nearly a two fold increase in cardiovascular events, independent of the presence of diabetes mellitus. [5] Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum triglyceride level, impaired fasting glucose, insulin resistance, or prediabetes. Metabolic syndrome, sometimes known by other names, is a clustering of at least three of the five following medical conditions: central obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). Metabolic Syndrome is a group of medical conditions that increases an individual’s risk of developing diabetes and coronary heart disease and increases their chances of … Metabolic syndrome is a name for a group of risk factors that occur together and increase the risk for coronary artery disease, stroke, and type 2 diabetes. – dyslipidaemia: TG ≥ 1.695 mmol/L Most patients are older, obese and have a degree of insulin resistance. The presence of metabolic syndrome is associated with a higher prevalence of CVD than found in people with type 2 diabetes or impaired glucose tolerance without the syndrome. The two differences are that IDF requires increased waist circumference, while NCEP does not and the IDF uses geography-specific cutpoints for waist circumference, while NCEP uses only one set of cutpoints for waist circumference regardless of geography. Psychopharmacology Metabolic syndrome On the Web Most recent articles. 1977 Apr 15; 32(8): 124-8. Hypothesis: Energy metabolism is associated with Vitamin D – April 2015. Most cited articles. Metabolt syndrom (Reavens syndrom X, insulinresistenssyndrom) är samlingsnamnet för ett antal faktorer som ökar risken för insjuknande i hjärt- och kärlsjukdomar.. De olika komponenterna i det metabola syndromet är var för sig oberoende riskfaktorer för hjärt-kärlsjukdom, men kombinationen av dem ökar den sammanlagda risken. … Found insideThis volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). [56] Diuretics and ACE inhibitors may be used to treat hypertension. Both genetic (e.g., Berardinelli-Seip congenital lipodystrophy, Dunnigan familial partial lipodystrophy) and acquired (e.g., HIV-related lipodystrophy in people treated with highly active antiretroviral therapy) forms of lipodystrophy may give rise to severe insulin resistance and many of metabolic syndrome's components. Buijs RM(1), Kreier F. Author information: (1)Universidad Veracruzana, Xalapa, Mexico. "Metabolic syndrome" 분류에 속하는 미디어 다음은 이 분류에 속하는 파일 4개 가운데 4개입니다. What are the symptoms of Metabolic syndrome? Both psoriasis and psoriatic arthritis have been found to be associated with metabolic syndrome. The metabolic syndrome seems to have 3 potential etiological categories: obesity and disorders of adipose tissue; insulin resistance; and a constellation of independent factors (eg, molecules of hepatic, vascular, and immunologic origin) that mediate specific components of the metabolic syndrome. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F. Diagnosis and Management of the Metabolic Syndrome. [28], There is research that associates comorbidity with rheumatic diseases. Plasma insulin above the 75th percentile of non-diabetic patients plus two of the following lead to a diagnosis of metabolic syndrome: Waist circumference 94 cm (37 inches) or greater in men, 80 cm (31 inches) or greater in women. 1 Battleground 2 Strategy 3 Walkthrough 4 Reference 1 Shibalien spawns after 20 seconds600f. The metabolic syndrome quintuples the risk of type 2 diabetes mellitus. Metabolic syndrome - Wikipedia. As part of the Core Handbook Series in Pediatrics, this book provides a practical discussion of the major endocrine disorders that can be managed in the primary care setting. A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity published a guideline to harmonize the definition of the metabolic syndrome. Metabolic Syndrome with and without obesity has low vitamin D - Oct 2016. Metabolic syndrome, longer life expectancy, and changes in diet are the most common risk factors. Kylin E: Studies of the hypertension-hyperglycemia-hyperuricemia syndrome. Metabolic syndrome, originally described by Reaven in 1988 as "syndrome X" or "insulin resistance syndrome", is a cluster of common abnormalities, including insulin resistance, impaired glucose tolerance, abdominal obesity, reduced high-density lipoprotein (HDL)-cholesterol levels, elevated triglycerides, and hypertension. Robert Lustig - What is Metabolic Syndrome Anyway? In 1988, in his Banting lecture, Dr. Gerald M. Reaven proposed insulin resistance as the underlying factor and named the constellation of abnormalities Syndrome X. Reaven did not include abdominal obesity, which has also been hypothesized as the underlying factor, as part of the condition. Clozapine, sold under the brand name Clozaril among others, is the first atypical antipsychotic medication. Also, the IDF uses geography-specific cut points for waist circumference, while NCEP uses only one set of cut points for waist circumference regardless of geography. CMS is now recognized as a disease entity by the World Health Organization and the American Society of Endocrinology. [33], Metabolic syndrome is seen to be a comorbidity in up to 50 percent of those with chronic obstructive pulmonary disease (COPD). CBD Store Capsules Metabolic Syndrome Wiki. It affects a large number of people in a clustered fashion. Metabolic syndrome is a combination of several medical issues. Metabolic syndrome is when your vital organs do not get sufficient energy to work optimally. Found inside – Page 81Metabolic. Syndrome. and. Pre-diabetes! ... every four people in the United States has metabolic syndrome (http://en.wikipedia.org/wiki/Metabolic_syndrome). When the base reaches 99% HP: 1 I.M. TIP: The Industrial-Organizational Psychologist, Tutorials in Quantitative Methods for Psychology, The role of psychologists in the management of metabolic disorder, Role of Fatty Acid Composition in the Development of Metabolic Disorders in Sucrose-Induced Obese Rats, http://www.idf.org/webdata/docs/IDF_Metasyndrome_definition.pdf. – blood pressure: ≥ 140/90 mmHg Plus 3 of the following: Fasting blood glucose >/= to 100 mg/dL or requiring treatment for elevated blood glucose. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. BP >/= 130/85 or requiring drug treatment for HTN. [29] In people with impaired glucose tolerance or impaired fasting glucose, presence of metabolic syndrome doubles the risk of developing type 2 diabetes. … Specialty. Asia Pac J Clin Nutr. Vague J. The International Diabetes Federation[43] consensus worldwide definition of metabolic syndrome (2006) is: [28], Physical inactivity is a predictor of CVD events and related mortality. [1][2] In the U.S., about 25% of the adult population has metabolic syndrome, a proportion increasing with age, particularly among racial and ethnic minorities.[3][4]. Extra weight around your waist (central or abdominal obesity). [37][38][39] Endocannabinoid overproduction may induce reward system dysfunction[38] and cause executive dysfunctions (e.g., impaired delay discounting), in turn perpetuating unhealthy behaviors. Banting lecture 1988. [41][39] Anandamide can also be produced from N-acylphosphatidylethanolamine via several pathways. Powerpoint slides. Condition of having high levels of urea in the blood. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology. Am J Clin Nutr 4:20-34, 1956. [49], Various strategies have been proposed to prevent the development of metabolic syndrome. [26] Psychosocial stress is also linked to heart disease. [34], It is common for there to be a development of visceral fat, after which the adipocytes (fat cells) of the visceral fat increase plasma levels of TNF-α and alter levels of other substances (e.g., adiponectin, resistin, and PAI-1). We have created a browser extension. This page was last edited on 11 September 2021, at 16:55, Berardinelli-Seip congenital lipodystrophy, National Heart, Lung, and Blood Institute, "A comprehensive review on metabolic syndrome", "Prevalence of metabolic syndrome and obesity-associated hypertension in the racial ethnic minorities of the United States", "Prevalence and trends of metabolic syndrome in the adult U.S. population, 1999–2010", "Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis", "Association of sedentary behaviour with metabolic syndrome: a meta-analysis", "Metabolic syndrome and metabolic abnormalities in patients with major depressive disorder: a meta-analysis of prevalences and moderating variables", "Adipose tissue expandability, lipotoxicity and the metabolic syndrome", "Toward a unifying hypothesis of metabolic syndrome", "Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress", "Targeting the consequences of the metabolic syndrome in the Diabetes Prevention Program", "The primary care physician's guide to inflammatory arthritis: diagnosis", "Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies", "Pharmacotherapeutic targeting of the endocannabinoid signaling system: drugs for obesity and the metabolic syndrome", "Formation and inactivation of endogenous cannabinoid anandamide in central neurons", "Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity", IDF Consensus Worldwide Definition of the Metabolic Syndrome, "Definition, Diagnosis, and Classification of Diabetes Mellitus and its Complications", "Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition", "Milk and dairy consumption, diabetes and the metabolic syndrome: the Caerphilly prospective study", "Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis", "Systematic Review of Metabolic Syndrome Biomarkers: A Panel for Early Detection, Management, and Risk Stratification in the West Virginian Population", "Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base", "Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US", "Persistent increase of prevalence of metabolic syndrome among U.S. adults: NHANES III to NHANES 1999-2006", "Continuous cardiometabolic risk score definitions in early childhood: a scoping review: Cardiometabolic risk definitions", "Early diagnosis of metabolic syndrome in children", "Relationship between serum sex hormones and glucose, insulin and lipid abnormalities in men with myocardial infarction", A man with marked central obesity, a hallmark of metabolic syndrome. metabolic disease a disease caused by some defect in the chemical reactions of the cells of the body. 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